Flamboyant Broadway renaissance man Peter Sellars was the director of The Cabinet of Dr. Ramirez. This freewheeling musical horror spoof isn't meant to be taken seriously, so don't be fooled by those Karloffian trappings. Ron Vawter plays the title character for all it's worth.
He has to, with such formidable competition as Joan Cusack, Mikhail Baryshnikov and Werner Klemperer, the latter cast as Fat Man Searching for a Tax Break. There's also a Beaver Gourmet in the cast of characters, which should clue you in as to the level of subtlety here.