In the aftermath of a comet breaking up over the Earth, most of the planet's population quickly succumb to a strange disease which turns them into 'zombies'. Few survive, and those who do quickly discover all existing fuel sources have been rendered unusable by the plague.
Trapped in a wilderness filled with living dead, unable to travel to any safer location, survivors have little to live for. One of those survivors, family man Barry has lost everything except his sister Brooke.
But even as the disaster unfolds, Brooke is kidnapped by a gang of paramilitary thugs and dragged off to a horrific medical lab run by a psychotic 'doctor' who is performing a series of deranged experiments on plague survivors.