Pat (Katharine Hepburn), a college phys-ed instructor, enters into professional competition as a golf and tennis player. Mike (Spencer Tracy), a likeable but unscrupulous sports promoter, first attempts to bribe Pat to lose, but later becomes her manager.
Pat performs brilliantly until her insufferable fiance Collier West (William Ching) shows up; West always manages to make Pat so nervous that she can't win to save her life. At long last, West walks out, having found Pat in a compromising situation with Mike.
Though she'd previously kept her distance from Mike, Pat suddenly realizes that she's fallen in love with him and--after a few crooked gamblers are disposed of--Pat and Mike become partners on a permanent basis. Pat & Mike reunited Tracy and Hepburn with their favorite director, George Cukor, and their favorite scenarists, Ruth Gordon and Garson Kanin.
Watch for real-life golf and tennis champs Gussie Moran, Babe Didrickson Zaharias, Don Budge, Alice Marble, Frank Parker, Betty Hicks, Helen Dettweilerand Beverly Hanson as themselves -- and also keep an eye out for ex-ballplayer Chuck Connors, making his acting debut as a highway patrolman.