Seymour Krelborn works and lives in a rundown flower shop on Skid Row. While his boss, Gravis Mushnick, struggles to keep the shop open, Seymour seeks a way of bringing the shop--and himself--fame and fortune. He purchases an exotic plant from an oriental street vendor, naming the plant Audrey II, after the girl he loves.
The plant proves good for business, attracting more customers to the store, but gradually Seymour learns to his horror that Audrey II craves blood and flesh, and Seymour must scare up human food to satisfy the plant's appetite. In the end, Seymour must confront the plant to secure a future of happiness with Audrey and to save all of mankind.