This sequel to Every Which Way But Loose finds Philo Beddoe (Clint Eastwood) on the road, orangutan companion Clyde in tow, as he makes his way as a bare-knuckle fighter. The action begins with Philo punching out a new victim while Clyde relieves himself on the seat of a police car, setting the tone for the rest of the story.
From there, Philo and Clyde return home, where Philo, who still lives with Ma (Ruth Gordon), is offered a contest with Jack Wilson (William Smith), the Mafia-sponsored East Coast bare-knuckle champ. Philo inadvertently saves Wilson's life, but then the Mafia kidnaps his girlfriend (Sondra Locke) to force him to go ahead with the match.
Philo and Wilson team up to battle the Mob, but somehow they end up fighting anyway in a grueling climactic sequence. Country music, bikers, the Mafia, an orangutan, pick-up trucks, defecation jokes, fighting, drinking, and swearing -- it's all here in this lowbrow comic stew.